Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4714075 | 0.91 | MAOA (0.59) | GFERHTR1DMAOAMAOBNISCH | |
| Hydrochloric Acid SCHEMBL27650682 | 0.91 | MAOA (0.59) | GFERHTR1DMAOAMAOBNISCH | |
| Hydrochloric Acid SCHEMBL4714070 | 0.90 | MAOA (0.58) | GFERHTR1DMAOAMAOBNISCH | |
| SCHEMBL12494943 | 0.81 | GFER (0.44) | GFERMAOAMAOBNISCHPTGIR | |
| SCHEMBL12495128 | 0.79 | GFER (0.40) | GFERHTR1DMAOAMAOBNISCH | |
| SCHEMBL30758863 | 0.78 | TSHR (0.69) | KCNJ1KCNH2TSHRSIGMAR1POLB | |
| SCHEMBL23097221 | 0.77 | HTR1D (0.60) | HTR1DMAOAMAOBNISCHTSHR | |
| SCHEMBL12495025 | 0.77 | RAD52 (0.57) | GFERHTR1DMAOAMAOBNISCH | |
| Hydrochloric Acid SCHEMBL3060877 | 0.77 | NISCH (0.61) | GFERMAOAMAOBNISCH | |
| SCHEMBL9575326 | 0.77 | NISCH (0.80) | HTR1DMAOAMAOBNISCHKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896437-B2 | Diarylhydantoin compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896437-B2 | Diarylhydantoin compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-20 | — | — | US | disclosed |
| US-20150065546-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-03-05 | — | — | US | disclosed |
| US-20150065546-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-03-05 | — | — | US | disclosed |
| US-20150065546-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-03-05 | — | — | US | disclosed |
| EP-2397469-B1 | Diarylhydantoin compounds | UNIV CALIFORNIA (US) | 2014-12-31 | — | — | EP | disclosed |
| EP-2397469-B1 | Diarylhydantoin compounds | UNIV CALIFORNIA (US) | 2014-12-31 | — | — | EP | disclosed |
| US-8680291-B2 | Diarylhydantoin compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-25 | — | — | US | disclosed |
| US-8680291-B2 | Diarylhydantoin compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-25 | — | — | US | disclosed |
| US-8680291-B2 | Diarylhydantoin compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-25 | — | — | US | disclosed |
| EP-2620432-A2 | Diarylhydantoin compounds | The Regents Of the University of California (US) | 2013-07-31 | — | — | EP | disclosed |
| EP-2397469-A1 | Diarylhydantoin compounds | The Regents Of the University of California (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-2397469-A1 | Diarylhydantoin compounds | The Regents Of the University of California (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-2220050-A2 | DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | The Regents Of The University Of California (US) | 2010-08-25 | — | — | EP | disclosed |
| US-20090111864-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-30 | — | — | US | disclosed |
| US-20090111864-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-30 | — | — | US | disclosed |
| WO-2009055053-A2 | DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009055053-A2 | DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065546-A1 | DIARYLHYDANTOIN COMPOUNDS | BPHL, ACP3, AR | GFER 3009/4885HTR1D 1773/4885MAOA 1281/4885 |
| US-20090111864-A1 | DIARYLHYDANTOIN COMPOUNDS | BPHL, ACP3, AR | GFER 3009/4885HTR1D 1773/4885MAOA 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.