Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721781 | 0.79 | GFER (0.54) | GFERPTGIRKCNJ1MAOAMAOB | |
| SCHEMBL12494943 | 0.75 | GFER (0.44) | GFERPTGIRMAPTMAOAMAOB | |
| SCHEMBL12495195 | 0.74 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAKCNJ1HIF1A | |
| Hydrochloric Acid SCHEMBL4714075 | 0.73 | MAOA (0.59) | GFERPTGIRKCNJ1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL27650682 | 0.73 | MAOA (0.59) | GFERPTGIRKCNJ1MAOAMAOB | |
| SCHEMBL15228300 | 0.73 | ALDH1A1 (0.54) | MAPTALDH1A1HIF1ATDP1 | |
| Hydrochloric Acid SCHEMBL4714070 | 0.72 | MAOA (0.58) | GFERPTGIRKCNJ1MAOAMAOB | |
| SCHEMBL15580197 | 0.72 | NPC1 (0.49) | MAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL5827781 | 0.72 | MAOA (0.57) | GFERMAPTLMNAMAOAMAOB | |
| SCHEMBL15496854 | 0.72 | ALDH1A1 (0.37) | MAPTALDH1A1LMNAKCNJ1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683694-B1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS INC (CN) | 2016-04-27 | — | — | EP | disclosed |
| EP-2683694-B1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS INC (CN) | 2016-04-27 | — | — | EP | disclosed |
| US-9216957-B2 | Androgen receptor antagonists and uses thereof | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2015-12-22 | — | — | US | disclosed |
| US-9216957-B2 | Androgen receptor antagonists and uses thereof | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2015-12-22 | — | — | US | disclosed |
| US-20140066425-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2014-03-06 | — | — | US | disclosed |
| US-20140066425-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2014-03-06 | — | — | US | disclosed |
| EP-2683694-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | Suzhou Kintor Pharmaceuticals,inc. (CN) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012119559-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS,INC. (CN) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012119559-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS,INC. (CN) | 2012-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066425-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | AR, SHBG, NR5A1 | GFER 575/4885PTGIR 123/4885MAPT 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.