Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721992 | 0.93 | BDKRB1 (0.35) | CNR1BDKRB1GAA | |
| SCHEMBL3728529 | 0.89 | MEN1 (0.43) | BDKRB1GAA | |
| SCHEMBL3722724 | 0.86 | MEN1 (0.36) | CNR1BDKRB1GAA | |
| SCHEMBL3722078 | 0.84 | BDKRB1 (0.40) | CNR1BDKRB1 | |
| SCHEMBL3725869 | 0.82 | MEN1 (0.42) | BDKRB1 | |
| SCHEMBL765813 | 0.81 | CNR1 (0.42) | CNR1BDKRB1 | |
| Trifluoroacetic Acid SCHEMBL3718216 | 0.81 | CNR1 (0.47) | CNR1BDKRB1 | |
| SCHEMBL3722860 | 0.80 | GAA (0.33) | GAA | |
| SCHEMBL3721990 | 0.79 | BDKRB1 (0.37) | CNR1BDKRB1 | |
| SCHEMBL3719005 | 0.77 | MAPK10 (0.35) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |