Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 8/20 | 0.35 |
| ▸ | CNR1 | P21554 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722079 | 0.93 | CNR1 (0.37) | BDKRB1CNR1GAA | |
| SCHEMBL3725869 | 0.90 | MEN1 (0.42) | BDKRB1TP53MAPK8MAPK10 | |
| SCHEMBL3721990 | 0.86 | BDKRB1 (0.37) | BDKRB1CNR1TP53 | |
| SCHEMBL3725887 | 0.82 | MAPK10 (0.31) | GAAMAPK8MAPK10 | |
| SCHEMBL3728529 | 0.82 | MEN1 (0.43) | BDKRB1GAAMAPK8MAPK10 | |
| SCHEMBL3722724 | 0.79 | MEN1 (0.36) | BDKRB1CNR1GAATP53MAPK8 | |
| SCHEMBL3722078 | 0.79 | BDKRB1 (0.40) | BDKRB1CNR1 | |
| Trifluoroacetic Acid SCHEMBL3718216 | 0.76 | CNR1 (0.47) | BDKRB1CNR1 | |
| SCHEMBL765813 | 0.76 | CNR1 (0.42) | BDKRB1CNR1 | |
| SCHEMBL3725868 | 0.75 | MEN1 (0.41) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |