Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795493 | 0.88 | GAA (0.34) | VNN1FAAHTRPV1 | |
| SCHEMBL3724203 | 0.88 | VNN1 (0.32) | VNN1FAAHTRPV1GRM5 | |
| SCHEMBL3724234 | 0.84 | GRM5 (0.35) | VNN1FAAHGRM5 | |
| SCHEMBL3725823 | 0.82 | ABL1 (0.38) | FAAHTRPV1 | |
| SCHEMBL3722860 | 0.82 | GAA (0.33) | VNN1FAAHTRPV1GRM5 | |
| SCHEMBL3722413 | 0.80 | CACNA1I (0.37) | VNN1FAAHTRPV1 | |
| SCHEMBL3725902 | 0.80 | CACNA1I (0.37) | VNN1FAAHTRPV1 | |
| SCHEMBL3727401 | 0.80 | MAPK8 (0.33) | VNN1FAAHTRPV1GRM5 | |
| SCHEMBL3725887 | 0.74 | MAPK10 (0.31) | — | |
| SCHEMBL185885 | 0.74 | FAAH (0.35) | FAAHTRPV1GRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |