Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12920429 | 0.89 | TP53 (0.57) | KDM4EALDH1A1MAPTTP53TSHR | |
| SCHEMBL12920452 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1MAPTTP53NPC1 | |
| SCHEMBL12920440 | 0.85 | MAPT (0.56) | KDM4EALDH1A1MAPTTP53TSHR | |
| SCHEMBL968281 | 0.85 | MYC (0.58) | KDM4EALDH1A1MAPTTP53TSHR | |
| SCHEMBL1505169 | 0.85 | MYC (0.58) | KDM4EALDH1A1MAPTTP53TSHR | |
| SCHEMBL969326 | 0.84 | SMN1; SMN2 (0.56) | KDM4EALDH1A1MAPTTP53TSHR | |
| SCHEMBL967418 | 0.84 | SMN1; SMN2 (0.56) | KDM4EALDH1A1MAPTTP53TSHR | |
| SCHEMBL3666883 | 0.84 | TP53 (0.52) | KDM4EALDH1A1MAPTTP53TSHR | |
| SCHEMBL10299345 | 0.83 | NPC1 (0.55) | KDM4EALDH1A1MAPTTP53TSHR | |
| SCHEMBL1008450 | 0.83 | KDM4E (0.64) | KDM4EALDH1A1MAPTTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569311-B1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RES INST (US) | 2016-01-13 | — | — | EP | disclosed |
| US-9133177-B2 | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RESEARCH CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133177-B2 | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RESEARCH CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| CN-102596945-A | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RES INS | 2012-07-18 | — | — | CN | disclosed |
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| CN-101952263-A | Romp-polymerizable electron transport materials based on a bis-oxadiazole moiety | GEORGIA TECH RES INST | 2011-01-19 | — | — | CN | disclosed |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2234991-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | Georgia Tech Research Corporation (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009080797-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD1, OCIAD2, OXA1L | KDM4E 4762/4885ALDH1A1 1850/4885MAPT 940/4885 |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD2, OCIAD1, ORC3 | KDM4E 4027/4885ALDH1A1 3486/4885MAPT 2091/4885 |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | SLCO1B3, SLCO4C1, SLCO2B1 | KDM4E 4711/4885ALDH1A1 1377/4885MAPT 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.