Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723774 | 0.92 | MTOR (0.61) | MTORPIK3CA | |
| SCHEMBL3727677 | 0.88 | MTOR (0.63) | MTORPIK3CA | |
| SCHEMBL3717802 | 0.85 | MTOR (0.56) | MTORPIK3CA | |
| SCHEMBL3723022 | 0.84 | MTOR (0.54) | MTORPIK3CA | |
| SCHEMBL3720180 | 0.83 | MTOR (0.60) | MTORPIK3CA | |
| SCHEMBL3721931 | 0.82 | MTOR (0.52) | MTORPIK3CA | |
| SCHEMBL3717169 | 0.81 | MTOR (0.60) | MTORPIK3CA | |
| SCHEMBL14843203 | 0.81 | MTOR (0.71) | MTORPIK3CA | |
| SCHEMBL3721782 | 0.80 | MTOR (0.63) | MTORPIK3CA | |
| SCHEMBL3729716 | 0.80 | MTOR (0.55) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120991-A1 | 5, 6, 7, 8-TETRAHYDROPYRIDO[4,3-D]PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR, PI3, AND HSMG-1 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH LLC (US) | 2010-10-21 | — | — | WO | disclosed |