Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 4/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421448 | 0.82 | KDM4E (0.33) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL6421451 | 0.82 | KDM4E (0.33) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL68934 | 0.81 | TSHR (0.46) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL6424408 | 0.78 | MAPK8 (0.35) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL6424410 | 0.78 | MAPK8 (0.35) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL5734466 | 0.75 | PTPN1 (0.42) | ALDH1A1POLBERN1TSHRKDM4E | |
| SCHEMBL31386711 | 0.74 | FABP6 (0.39) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL2394883 | 0.74 | MAPK8 (0.43) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL2619615 | 0.74 | CYP2A6 (0.45) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL13913259 | 0.74 | PTPN1 (0.46) | ALDH1A1POLBLMNATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806568-A | Method for constructing heteroatom substituted xanthene derivative through palladium-catalyzed cross coupling and application | 华东师范大学 | 2023-03-17 | — | — | CN | disclosed |
| WO-2010120345-A1 | METABOLICALLY INERT ANTIFOLATES: NEW INDICATIONS AND FORMULATIONS | NAIR MADHAVAN G (US) | 2010-10-21 | — | — | WO | disclosed |
| US-20100260825-A1 | Antifolates for the treatment of cardiovascular, inflammatory, neoplastic, autoimmune and related diseases in sublingual dosage units, film strips, or skin patches | NAIR MADHAVAN G | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100260825-A1 | Antifolates for the treatment of cardiovascular, inflammatory, neoplastic, autoimmune and related diseases in sublingual dosage units, film strips, or skin patches | SLC19A1, TPMT, DHFR | ALDH1A1 851/4885POLB 2288/4885RAB9A 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.