SCHEMBL68934

SCHEMBL68934

COC(=O)c1cscc1C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
LMNA P02545 1/20 0.46
ALDH1A1 P00352 3/20 0.45
HSD17B10 Q99714 2/20 0.45
CFTR P13569 1/20 0.45
KDM4E B2RXH2 5/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA9 Q16790 3/20 0.43
CA12 O43570 2/20 0.43
CA7 P43166 2/20 0.43
CA14 Q9ULX7 2/20 0.43
ATM Q13315 2/20 0.43
POLB P06746 1/20 0.43
PDK2 Q15119 1/20 0.43
PDK4 Q16654 1/20 0.43
MAPK8 P45983 1/20 0.42
MAPK9 P45984 1/20 0.42
MAPK10 P53779 1/20 0.42
CHEK1 O14757 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13913259 0.91 PTPN1 (0.46) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL3056644 0.89 TSHR (0.39) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL8197514 0.86 LMNA (0.50) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL2619615 0.86 CYP2A6 (0.45) TSHRLMNAALDH1A1HSD17B10CFTR
Cyclopropane SCHEMBL11664340 0.85 PTPN1 (0.42) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL28651663 0.85 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10KDM4E
SCHEMBL17918611 0.84 TSHR (0.39) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL16289854 0.84 TSHR (0.39) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL18047964 0.84 GSK3B (0.52) TSHRLMNAALDH1A1HSD17B10CFTR
Hydrochloric Acid SCHEMBL31319493 0.84 CYP2A6 (0.44) TSHRLMNAALDH1A1HSD17B10CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119176892-A Ziegler-Navigator catalyst 中国科学院大连化学物理研究所 2024-12-24 CN claimed
US-20250215004-A1 AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES GEORG-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS (DE) 2025-07-03 US disclosed
EP-4559521-A2 AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin (DE) 2025-05-28 EP disclosed
EP-4404931-B1 AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES GEORG AUGUST UNIV GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS UNIVSMEDIZIN (DE) 2025-04-09 EP disclosed
CN-119176892-A Ziegler-Navigator catalyst 中国科学院大连化学物理研究所 2024-12-24 CN disclosed
WO-2024227701-A1 PYRIDAZINE COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES Tietze Chemical Consulting UG (haftungsbeschränkt) (DE) 2024-11-07 WO disclosed
EP-4458358-A1 PYRIDAZINE COMPOUNDS FOR ANTIFIBROTIC THERAPY Tietze Chemical Consulting UG (DE) 2024-11-06 EP disclosed
EP-4404931-A1 AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin (DE) 2024-07-31 EP disclosed
CN-117304459-B Bio-based sulfur-containing high-refraction polyester and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-04-19 CN disclosed
CN-117304459-A Bio-based sulfur-containing high-refraction polyester and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-12-29 CN disclosed
US-8968885-B2 Organic electronic devices and polymers, including photovoltaic cells and diketone-based polymers SOLVAY USA, INC. (US) 2015-03-03 US disclosed
US-8968885-B2 Organic electronic devices and polymers, including photovoltaic cells and diketone-based polymers SOLVAY USA, INC. (US) 2015-03-03 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110204341-A1 ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED POLYMERS PLEXTRONICS, INC. 2011-08-25 US disclosed
US-20110204341-A1 ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED POLYMERS PLEXTRONICS, INC. 2011-08-25 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
WO-2011028827-A2 ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED POLYMERS PLEXTRONICS, INC. (US) 2011-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TSHR 3263/4885LMNA 2207/4885ALDH1A1 1882/4885
US-20250215004-A1 AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES COL1A1, COL14A1, COL2A1 TSHR 4337/4885LMNA 1712/4885ALDH1A1 747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.