Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | KDM1A | O60341 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366374 | 0.71 | HTR2C (0.53) | HTR2CKDM1AMAOBKIF11 | |
| SCHEMBL19733862 | 0.69 | HTR2C (0.53) | HTR2CKDM1AMAOBRCOR1KIF11 | |
| SCHEMBL13742154 | 0.68 | HTR2C (0.87) | HTR2CKDM1AMAOBHTR2AHTR2B | |
| SCHEMBL2231911 | 0.68 | HTR2C (0.49) | HTR2CKDM1AMAOBRCOR1 | |
| SCHEMBL1847401 | 0.67 | HTR2C (0.73) | HTR2CKDM1AMAOBMAOA | |
| SCHEMBL3123347 | 0.67 | HTR2C (0.61) | HTR2CKIF11 | |
| Hydrochloric Acid SCHEMBL4139504 | 0.67 | HTR2C (0.90) | HTR2CMAOBHTR2AHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL4139502 | 0.67 | HTR2C (0.90) | HTR2CMAOBHTR2AHTR2BSLC6A3 | |
| SCHEMBL12032020 | 0.66 | ALDH1A1 (0.47) | HTR2CKDM1ARCOR1KIF11 | |
| SCHEMBL2299932 | 0.66 | LTA4H (0.47) | KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136128-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |