Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.57 |
| ▸ | RXRG | P48443 | 10/20 | 0.57 |
| ▸ | RXRB | P28702 | 9/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.57 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.57 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.57 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.57 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.57 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178691 | 0.85 | RXRA (0.70) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL30646805 | 0.85 | RXRA (0.50) | RXRARXRGRXRBCYP11B1CYP11B2 | |
| SCHEMBL29087758 | 0.85 | RXRA (0.50) | RXRARXRGRXRBCYP11B1CYP11B2 | |
| SCHEMBL9926848 | 0.83 | CYP11B1 (0.60) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL29617616 | 0.83 | CYP11B1 (0.60) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL24499977 | 0.83 | CYP11B2 (0.57) | RXRARXRGRXRBCYP11B1CYP11B2 | |
| SCHEMBL30530575 | 0.83 | CYP11B2 (0.57) | RXRARXRGRXRBCYP11B1CYP11B2 | |
| SCHEMBL491483 | 0.83 | RXRA (0.71) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL4591858 | 0.81 | CYP11B1 (0.51) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL2272003 | 0.81 | RXRA (0.77) | RXRARXRGRXRBPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| US-20120149694-A1 | Substituted piperidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149694-A1 | Substituted piperidines | VHL, PIR, PIGO | RXRA 1842/4885RXRG 2353/4885RXRB 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.