Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 16/20 | 0.77 |
| ▸ | ADRB2 | P07550 | 15/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.77 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.77 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.77 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | HTR1A | P08908 | 2/20 | 0.77 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.77 |
| ▸ | DRD3 | P35462 | 2/20 | 0.77 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.77 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199075 | 0.90 | ADRB2 (0.63) | ADRB1ADRB2ADRA1AADRA1DADRA1B | |
| SCHEMBL3722140 | 0.90 | ADRB2 (0.67) | ADRB1ADRB2ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL3719742 | 0.89 | ADRB2 (0.84) | ADRB1ADRB2ADRA1AADRA1DADRA1B | |
| SCHEMBL13284845 | 0.88 | ADRB2 (0.80) | ADRB1ADRB2ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL3719745 | 0.88 | ADRB2 (0.82) | ADRB1ADRB2ADRA1AADRA1DADRA1B | |
| Dilevalol SCHEMBL79468 | 0.87 | ADRB1 (1.00) | ADRB1ADRB2ADRA1AADRA1DADRA1B | |
| Labetalol SCHEMBL10356800 | 0.87 | ADRB1 (1.00) | ADRB1ADRB2ADRA1AADRA1DADRA1B | |
| Labetalol SCHEMBL10882744 | 0.87 | ADRB1 (1.00) | ADRB1ADRB2ADRA1AADRA1DADRA1B | |
| Labetalol SCHEMBL41231 | 0.87 | ADRB1 (1.00) | ADRB1ADRB2ADRA1AADRA1DADRA1B | |
| Labetalol SCHEMBL7273474 | 0.87 | ADRB1 (1.00) | ADRB1ADRB2ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129987-A1 | NOVEL RECEPTOR HETERO-DIMERS/-OLIGOMERS | DIMERIX BIOSCIENCE PTY LTD (AU) | 2010-11-18 | — | — | WO | disclosed |