Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | DRD3 | P35462 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16858630 | 0.93 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL3723459 | 0.90 | ADRB1 (0.77) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL11199075 | 0.88 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL16858628 | 0.88 | ADRB2 (0.64) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL3720694 | 0.87 | ADRB2 (0.59) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL7208690 | 0.87 | ADRB2 (0.80) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL7208694 | 0.87 | ADRB2 (0.80) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| Water SCHEMBL29020001 | 0.85 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL11810215 | 0.85 | ADRB2 (0.73) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL721150 | 0.84 | ADRB2 (0.69) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999134-B | Preparation method of formoterol, pharmaceutically acceptable salts thereof and intermediates thereof | 广州呼吸药物工程技术有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-113999134-A | Preparation method of formoterol, medicinal salt and intermediate thereof | 广州健康元呼吸药物工程技术有限公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2010129987-A1 | NOVEL RECEPTOR HETERO-DIMERS/-OLIGOMERS | DIMERIX BIOSCIENCE PTY LTD (AU) | 2010-11-18 | — | — | WO | disclosed |
| EP-2077830-A1 | METHODS, COMPOSITIONS, AND FORMULATIONS FOR THE TREATMENT OF THYROID EYE DISEASE | Lithera, Inc. (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008048770-A1 | METHODS, COMPOSITIONS, AND FORMULATIONS FOR THE TREATMENT OF THYROID EYE DISEASE | LIPOTHERA, INC. (US) | 2008-04-24 | — | — | WO | disclosed |