Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19233450 | 0.84 | ACE2 (0.44) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL11775378 | 0.83 | CHRM1 (0.42) | ACE2GRIK1GRIK2 | |
| SCHEMBL28672919 | 0.82 | GPR84 (0.52) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL28878400 | 0.81 | FFAR4 (0.50) | GPR84FFAR1FFAR4 | |
| Acetic Acid SCHEMBL31579080 | 0.80 | CHRNB2 (0.50) | ACE2GPR84FFAR1MAPTLCK | |
| Oxalic Acid SCHEMBL11335719 | 0.80 | CHRNB2 (0.50) | ACE2GPR84FFAR1MAPTLCK | |
| Oxalic Acid SCHEMBL11335711 | 0.80 | CHRNB2 (0.50) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL9422722 | 0.79 | FAAH (0.44) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL11051781 | 0.78 | ACE2 (0.47) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL8691267 | 0.78 | GPR84 (0.48) | ACE2GPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393809-A2 | DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089510-A2 | DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-08-12 | — | — | WO | disclosed |