Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855973 | 0.91 | ALDH1A1 (0.52) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL3722341 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GSTP1GSTM2KMT2AMAPT | |
| SCHEMBL27223853 | 0.81 | ALDH1A1 (0.54) | ALDH1A1GSTP1GSTM2KMT2AMAPT | |
| SCHEMBL2437569 | 0.80 | TDP1 (0.44) | ALDH1A1GSTP1GSTM2KMT2AMAPT | |
| SCHEMBL30733389 | 0.80 | MAPT (0.33) | ALDH1A1GSTP1GSTM2KMT2AMAPT | |
| SCHEMBL26695852 | 0.80 | MAPT (0.33) | ALDH1A1GSTP1GSTM2KMT2AMAPT | |
| SCHEMBL2761732 | 0.79 | SLC6A3 (0.48) | ALDH1A1KMT2AMAPTLMNAADRB2 | |
| SCHEMBL12381878 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL16064422 | 0.78 | ALDH1A1 (0.54) | ALDH1A1GSTP1GSTM2KMT2AMAPT | |
| SCHEMBL20703719 | 0.76 | MAPT (0.41) | ALDH1A1GSTP1GSTM2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101838218-A | Ester compound and pharmaceutical use of the same | JAPAN TOBACCO INC | 2010-09-22 | — | — | CN | disclosed |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. | 2010-06-24 | — | — | US | disclosed |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. | 2010-06-24 | — | — | US | disclosed |
| CN-1630629-B | Ester compound and medical use thereof | JAPAN TOBACCO INC | 2010-05-05 | — | — | CN | disclosed |
| US-7625948-B2 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-7625948-B2 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-7432392-B2 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-20060205726-A1 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1669345-A1 | ESTER DERIVATIVE AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2006-06-14 | — | — | EP | disclosed |
| CN-1630629-A | Ester compound and medical use thereof | JAPAN TOBACCO INC (JP) | 2005-06-22 | — | — | CN | disclosed |
| US-20050075367-A1 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | US | disclosed |
| EP-1479666-A1 | ESTER COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205726-A1 | Ester derivatives and medical use thereof | MTTP, LIPC, CETP | ALDH1A1 733/4885GSTP1 291/4885GSTM2 353/4885 |
| US-20050075367-A1 | Ester compound and medicinal use thereof | LIPC, CES1, MTTP | ALDH1A1 564/4885GSTP1 2079/4885GSTM2 1579/4885 |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | LIPC, CES1, MTTP | ALDH1A1 603/4885GSTP1 1920/4885GSTM2 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.