Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.66 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390123 | 1.00 | GRIK1 (0.66) | GRIK1ALPIPKMPTGS1XIAP | |
| SCHEMBL28465699 | 1.00 | GRIK1 (0.66) | GRIK1ALPIPKMPTGS1XIAP | |
| SCHEMBL17686506 | 0.98 | GRIK1 (0.64) | GRIK1ALPIPKMPTGS1XIAP | |
| SCHEMBL3664379 | 0.98 | GRIK1 (0.64) | GRIK1ALPIPKMPTGS1XIAP | |
| SCHEMBL28469566 | 0.98 | GRIK1 (0.64) | GRIK1ALPIPKMPTGS1XIAP | |
| SCHEMBL24816430 | 0.98 | GRIK1 (0.64) | GRIK1ALPIPKMPTGS1XIAP | |
| SCHEMBL23176817 | 0.98 | GRIK1 (0.64) | GRIK1ALPIPKMPTGS1XIAP | |
| SCHEMBL17686507 | 0.98 | GRIK1 (0.64) | GRIK1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL27330363 | 0.98 | GRIK1 (0.64) | GRIK1ALPIPKMPTGS1XIAP | |
| SCHEMBL3664561 | 0.98 | GRIK1 (0.64) | GRIK1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148312-A1 | COMPOSITIONS, SYSTEMS, AND METHODS FOR AMINO ACID SYNTHESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-11 | — | — | WO | claimed |
| EP-1165491-B1 | LTA4 HYDROLASE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2004-02-11 | — | — | EP | claimed |
| US-20030032774-A1 | Novel opioid peptides for the treatment of pain | ASTRAZENECA AB | 2003-02-13 | — | — | US | claimed |
| EP-1164141-A2 | Opioid peptides and their use for treatment of pain | AstraZeneca AB (SE) | 2001-12-19 | — | — | EP | claimed |
| WO-2024148312-A1 | COMPOSITIONS, SYSTEMS, AND METHODS FOR AMINO ACID SYNTHESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-11 | — | — | WO | disclosed |
| CN-114401633-A | Pest control method, pest control agent composition, and pest control agent set | 日本曹达株式会社 | 2022-04-26 | — | — | CN | disclosed |
| CN-111777521-A | Synthesis method of multi-configuration long-chain phenyl amino acid compound | 苏州爱玛特生物科技有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-106749373-B | Rubber additive and preparation and application thereof | 同济大学 | 2020-06-26 | — | — | CN | disclosed |
| EP-2409569-B1 | Method for administering GLP-1 molecules | EMISPHERE TECH INC (US) | 2017-08-16 | — | — | EP | disclosed |
| US-9649373-B2 | Neoseptins: small molecule adjuvants | THE SCRIPPS INSTITUTE (US) | 2017-05-16 | — | — | US | disclosed |
| US-9649373-B2 | Neoseptins: small molecule adjuvants | THE SCRIPPS INSTITUTE (US) | 2017-05-16 | — | — | US | disclosed |
| EP-2958889-B1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | SCRIPPS RESEARCH INST (US) | 2017-03-22 | — | — | EP | disclosed |
| WO-1998034632-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-08-13 | — | — | WO | disclosed |
| US-5776888-A | 3-(DIMETHOXYBENZOYLAMINOPHENYL) PROPIONIC ACID | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5773647-A | USING A AROMATIC COMPOUND CONTAINING AMIDE AND CARBOXY GROUPS | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |
| CN-1039596-A | Preparation method in conjunction with the peptide of retroviral Protease | SMITHKLINE BECKMAN CORP (US) | 1990-02-14 | — | — | CN | disclosed |
| EP-0226636-B1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0226636-A1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1987-07-01 | — | — | EP | disclosed |
| WO-1987000521-A2 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1987-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032774-A1 | Novel opioid peptides for the treatment of pain | OPRL1, OPRK1, OPRM1 | GRIK1 291/4885ALPI 4275/4885PKM 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.