Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | NOS1 | P29475 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664379 | 1.00 | GRIK1 (0.64) | GRIK1POLBKMT2ATDP1S1PR2 | |
| SCHEMBL17686506 | 1.00 | GRIK1 (0.64) | GRIK1POLBKMT2ATDP1S1PR2 | |
| SCHEMBL17686507 | 1.00 | GRIK1 (0.64) | GRIK1POLBKMT2ATDP1S1PR2 | |
| SCHEMBL28469566 | 1.00 | GRIK1 (0.64) | GRIK1POLBKMT2ATDP1S1PR2 | |
| SCHEMBL23176817 | 1.00 | GRIK1 (0.64) | GRIK1POLBKMT2ATDP1S1PR2 | |
| SCHEMBL24816430 | 1.00 | GRIK1 (0.64) | GRIK1POLBKMT2ATDP1S1PR2 | |
| SCHEMBL3390123 | 0.98 | GRIK1 (0.66) | GRIK1POLBKMT2ATDP1S1PR2 | |
| SCHEMBL28465699 | 0.98 | GRIK1 (0.66) | GRIK1POLBKMT2ATDP1S1PR2 | |
| SCHEMBL372365 | 0.98 | GRIK1 (0.66) | GRIK1POLBKMT2ATDP1S1PR2 | |
| Hydrochloric Acid SCHEMBL27330363 | 0.96 | GRIK1 (0.64) | GRIK1POLBKMT2ATDP1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411362-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-GEN THERAPEUTICS, INC. | 2022-12-29 | — | — | US | disclosed |
| US-9957286-B2 | Method for the synthesis of solid heterogeneous chiral catalysts and their use in stereoselective reactions | UNIVERSIDAD DE GUANAJUATO (MX) | 2018-05-01 | — | — | US | disclosed |
| US-20170145041-A1 | METHOD FOR THE SYNTHESIS OF SOLID HETEROGENEOUS CHIRAL CATALYSTS AND THEIR USE IN STEREOSELECTIVE REACTIONS | UNIV GUANAJUATO (MX) | 2017-05-25 | — | — | US | disclosed |
| CN-101970682-B | Method for detecting and/or identifying clostridium difficile | BIOMERIEUX SA | 2015-05-13 | — | — | CN | disclosed |
| EP-2235202-B1 | METHOD FOR DETECTING AND/OR IDENTIFYING CLOSTRIDIUM DIFFICILE | BIOMERIEUX SA (FR) | 2013-06-19 | — | — | EP | disclosed |
| US-8404460-B2 | Method for detecting and/or identifying Clostridium difficile | BIOMERIEUX (FR) | 2013-03-26 | — | — | US | disclosed |
| CN-101970682-A | Method for detecting and/or identifying clostridium difficile | BIOMERIEUX SA | 2011-02-09 | — | — | CN | disclosed |
| US-20100279330-A1 | METHOD FOR DETECTING AND/OR IDENTIFYING CLOSTRIDIUM DIFFICILE | BIOMERIEUX (FR) | 2010-11-04 | — | — | US | disclosed |
| EP-2235202-A2 | METHOD FOR DETECTING AND/OR IDENTIFYING CLOSTRIDIUM DIFFICILE | Biomérieux (FR) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009092982-A2 | METHOD FOR DETECTING AND/OR IDENTIFYING CLOSTRIDIUM DIFFICILE | bioMérieux (FR) | 2009-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411362-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | PRKCA, PRKCH, PRKCB | GRIK1 1918/4885POLB 2482/4885KMT2A 2943/4885 |
| US-20170145041-A1 | METHOD FOR THE SYNTHESIS OF SOLID HETEROGENEOUS CHIRAL CATALYSTS AND THEIR USE IN STEREOSELECTIVE REACTIONS | MCM4, DCXR, MCM6 | GRIK1 2814/4885POLB 643/4885KMT2A 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.