Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724749 | 0.83 | ACACB (0.45) | MTNR1AMTNR1BSMN1; SMN2ACACBKDM4E | |
| SCHEMBL3717195 | 0.82 | MAPK1 (0.45) | MTNR1AMTNR1BSMN1; SMN2ACACB | |
| SCHEMBL3720776 | 0.81 | PLAAT3 (0.48) | MTNR1AMTNR1BSMN1; SMN2ACACB | |
| SCHEMBL3717145 | 0.81 | KDM4E (0.43) | MTNR1AMTNR1BSMN1; SMN2ACACBKDM4E | |
| SCHEMBL3719665 | 0.81 | ACACB (0.54) | MTNR1AMTNR1BSMN1; SMN2ACACBKDM4E | |
| SCHEMBL3727291 | 0.81 | KDM4E (0.50) | MTNR1AMTNR1BSMN1; SMN2ACACBKDM4E | |
| SCHEMBL3720624 | 0.81 | ALDH1A1 (0.49) | MTNR1AMTNR1BSMN1; SMN2ACACBALDH1A1 | |
| SCHEMBL3718523 | 0.80 | PARG (0.34) | KDM4EPARG | |
| SCHEMBL3718519 | 0.80 | ESRRA (0.47) | SMN1; SMN2ALDH1A1MAPTPARG | |
| SCHEMBL3722351 | 0.80 | SMN1; SMN2 (0.54) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |