Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3723735 | 0.79 | KDM1A (0.31) | — | |
| SCHEMBL289185 | 0.78 | CYP1A2 (0.30) | — | |
| SCHEMBL4163760 | 0.74 | USP19 (0.39) | TSHR | |
| SCHEMBL10127159 | 0.73 | CYP3A4 (0.34) | — | |
| SCHEMBL6618863 | 0.71 | TSHR (0.44) | TSHR | |
| SCHEMBL10111396 | 0.71 | TSHR (0.39) | TSHR | |
| Hydrochloric Acid SCHEMBL18690044 | 0.70 | TSHR (0.41) | TSHR | |
| SCHEMBL20941865 | 0.67 | OPRM1 (0.34) | TSHR | |
| SCHEMBL20941868 | 0.66 | PIK3CD (0.39) | TSHR | |
| SCHEMBL347358 | 0.66 | CTSB (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129729-A1 | SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2010-11-11 | — | — | WO | disclosed |