Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TEC | P42680 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720790 | 0.92 | CSNK2A1 (0.41) | ACACBCSNK2A1PPARDPPARAP2RX3 | |
| SCHEMBL3724495 | 0.88 | PDE3B (0.34) | ACACBACACAPPARDPDE3BPDE3A | |
| SCHEMBL3721014 | 0.88 | ACACB (0.41) | ACACBACACACYP3A4CYP2C9TEC | |
| SCHEMBL3719552 | 0.87 | PDE3B (0.34) | ACACBACACAPDE3BPDE3A | |
| SCHEMBL3717771 | 0.87 | MEN1 (0.37) | ACACBACACACYP3A4PDE3BPDE3A | |
| SCHEMBL3723787 | 0.86 | ACACB (0.44) | ACACBTECPDE3BPDE3A | |
| SCHEMBL3726328 | 0.85 | ACACB (0.40) | ACACBACACACYP3A4PDE3BPDE3A | |
| SCHEMBL3720774 | 0.85 | GLA (0.43) | ACACBCSNK2A1CYP3A4TEC | |
| SCHEMBL3720016 | 0.85 | RXRA (0.39) | P2RX3 | |
| SCHEMBL3722838 | 0.84 | CSNK2A1 (0.40) | ACACBCSNK2A1PPARDPPARAPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |