Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TEC | P42680 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718574 | 0.92 | GLA (0.53) | SMN1; SMN2GLAACACBTECCSNK2A1 | |
| SCHEMBL3723730 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2GLAACACBKMT2ATEC | |
| SCHEMBL3725388 | 0.89 | GLA (0.44) | SMN1; SMN2GLAACACBTECCSNK2A1 | |
| SCHEMBL3717501 | 0.87 | GLA (0.39) | SMN1; SMN2GLAKMT2ANCF1CYP3A4 | |
| SCHEMBL3717279 | 0.86 | GLA (0.57) | SMN1; SMN2GLAACACBTECCSNK2A1 | |
| SCHEMBL3720774 | 0.86 | GLA (0.43) | SMN1; SMN2GLAACACBKMT2ATEC | |
| SCHEMBL3718627 | 0.85 | ACACB (0.43) | SMN1; SMN2GLAACACBTECCYP3A4 | |
| SCHEMBL3723787 | 0.85 | ACACB (0.44) | SMN1; SMN2ACACBKMT2ATECALDH1A1 | |
| SCHEMBL3723076 | 0.83 | MTNR1A (0.50) | SMN1; SMN2ACACBALDH1A1 | |
| SCHEMBL3719951 | 0.82 | CSNK2A1 (0.47) | SMN1; SMN2GLAACACBKMT2ATEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |