Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714673 | 0.81 | TSHR (0.43) | ENPP2IDO1AGXTCA4CYP1A2 | |
| SCHEMBL3658498 | 0.79 | IDO1 (0.40) | ENPP2MAOBIDO1AGXTCA4 | |
| SCHEMBL22960766 | 0.77 | MAOB (0.59) | ENPP2MAOBBCHEGAA | |
| SCHEMBL18587051 | 0.77 | IDO1 (0.47) | MAOBIDO1TAAR1 | |
| SCHEMBL18587306 | 0.74 | NPC1 (0.42) | MAOBAGXT | |
| SCHEMBL18587216 | 0.74 | IDO1 (0.47) | MAOBIDO1AGXT | |
| SCHEMBL14237388 | 0.72 | ENPP2 (0.57) | ENPP2CA4 | |
| SCHEMBL6586812 | 0.72 | ENPP2 (0.53) | ENPP2ABCB1HTR1AMRGPRX4 | |
| SCHEMBL480132 | 0.72 | ENPP2 (0.67) | ENPP2CA4TAAR1 | |
| SCHEMBL28041771 | 0.72 | ENPP2 (0.67) | ENPP2CA4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138576-A1 | PYRIMIDINE INHIBITORS OF KINASE ACTIVITY | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | disclosed |