Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480132 | 0.81 | ENPP2 (0.67) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL27951222 | 0.81 | ENPP2 (0.67) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL28329900 | 0.81 | ENPP2 (0.67) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5665659 | 0.81 | ENPP2 (0.67) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL20595738 | 0.80 | CA1 (0.61) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5140 | 0.80 | ENPP2 (1.00) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7344145 | 0.80 | ENPP2 (1.00) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7344156 | 0.80 | ENPP2 (0.65) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL12524808 | 0.79 | ENPP2 (0.74) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| Methyl Alcohol SCHEMBL28712606 | 0.79 | ENPP2 (0.96) | ENPP2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801550-B | Novel chromene kinase modulator | 理森制药股份公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109803651-A | Immunomodulator compounds | 凯莫森特里克斯股份有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-107428744-A | Novel heterocyclic compounds and its application in medicine and cosmetics | 盖尔德马研究及发展公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-102977036-B | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | 美国陶氏益农公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-105801550-A | Novel benzopyran kinase modulators | 理森制药股份公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-103958475-B | Heteroaryl hydroxamic acid derivatives and their use in the treatment, alleviation or prevention of viral diseases | F. HOFFMANN-LA ROCHE AG (CH) | 2015-11-25 | — | — | CN | disclosed |