Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041771 | 0.81 | ENPP2 (0.67) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL27951222 | 0.81 | ENPP2 (0.67) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5665659 | 0.81 | ENPP2 (0.67) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL28329900 | 0.81 | ENPP2 (0.67) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5140 | 0.80 | ENPP2 (1.00) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7344145 | 0.80 | ENPP2 (1.00) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL6522357 | 0.80 | CA1 (0.61) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7344156 | 0.80 | ENPP2 (0.65) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL12524808 | 0.79 | ENPP2 (0.74) | ENPP2PRSS1PRSS2PRSS3CA1 | |
| Methyl Alcohol SCHEMBL28712606 | 0.79 | ENPP2 (0.96) | ENPP2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204498-A | A method of it efficiently synthesizes and dislikes La Geli intermediate | 奥锐特药业股份有限公司 | 2019-09-06 | — | — | CN | claimed |
| CN-109415319-A | Synthesizing aryl carboxylate is coupled by direct Su Chuji | 美国陶氏益农公司 | 2019-03-01 | — | — | CN | claimed |
| CN-103827124-B | Method and system for forming boric acid class and its intermediate | 陶氏益农公司 | 2017-06-06 | — | — | CN | claimed |
| CN-103814034-B | Method for separating 4-chloro-2-fluoro-3-substituted-phenylboronic acid | 陶氏益农公司 | 2017-02-15 | — | — | CN | claimed |
| CN-103864750-A | Derivative of N-biphenyl dichloroacetamide as well as preparation method and applications thereof | UNIV TSINGHUA | 2014-06-18 | — | — | CN | claimed |
| CN-110498771-A | A method of preparing the intermediate for disliking La Geli | SHANGHAI INST PHARMACEUTICAL IND | 2019-11-26 | — | — | CN | disclosed |
| CN-110498770-A | A method of it prepares and dislikes La Geli intermediate | SHANGHAI INST PHARMACEUTICAL IND | 2019-11-26 | — | — | CN | disclosed |
| CN-110437159-A | The preparation method of antagonists of gonadotropin-releasing hormone intermediate and antagonist sodium | LIVZON NEW NORTH RIVER PHARMACEUTICAL CO LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-110204498-A | A method of it efficiently synthesizes and dislikes La Geli intermediate | 奥锐特药业股份有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-106536508-B | For treat Alzheimer disease have the active compound of cholinergic muscarinic M1 receptor positive allosteric regulator | 武田药品工业株式会社 | 2019-08-09 | — | — | CN | disclosed |
| CN-110092774-A | Fragrant propionic acid analog derivative, and its preparation method and application | 中国科学院上海药物研究所 | 2019-08-06 | — | — | CN | disclosed |
| CN-110066236-A | 1H- azole derivatives, preparation method, pharmaceutical composition and application | 上海迪诺医药科技有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-102786480-A | 2-substituted-6-amino-5-alkyl, alkenyl or alkynyl-4-pyrimidinecarboxylic acids and 6-substituted-4-amino-3- alkyl, alkenyl or alkynyl picolinic acids and their use as herbicides | DOW AGROSCIENCES LLC | 2012-11-21 | — | — | CN | disclosed |
| CN-102395568-A | Pyrimidine derivatives and their use as herbicides | SYNGENTA LTD | 2012-03-28 | — | — | CN | disclosed |
| CN-102356068-A | 2,3-diaryl- or heteroaryl-substituted 1,1,1-trifluoro-2-hydroxypropyl compounds | HOFFMANN LA ROCHE | 2012-02-15 | — | — | CN | disclosed |
| EP-2411361-A1 | 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2012-02-01 | — | — | EP | disclosed |
| CN-102083835-A | Bridged, bicyclic heterocyclic or spiro bicyclic heterocyclic derivatives of pyrazolo[1,5-A]pyrimidines, methods for preparation and uses thereof | WYETH CORP | 2011-06-01 | — | — | CN | disclosed |
| WO-2011002408-A1 | NOVEL COMPOUNDS FOR TREATMENT OF NEURODEGENERATION ASSOCIATED WITH DISEASES, SUCH AS ALZHEIMER'S DISEASE OR DEMENTIA | ASTRAZENECA AB (SE) | 2011-01-06 | — | — | WO | disclosed |
| WO-2010108902-A1 | 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-30 | — | — | WO | disclosed |
| CN-101675053-A | Phosphoinositide 3-kinase inhibitor compounds and methods of use | GENENTECH INC | 2010-03-17 | — | — | CN | disclosed |