Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723983 | 1.00 | LMNA (0.42) | LMNAGAAMAPTTDP1ALDH1A1 | |
| SCHEMBL2018224 | 0.86 | LMNA (0.47) | LMNAGAAMAPTALDH1A1 | |
| SCHEMBL692372 | 0.82 | CA9 (0.35) | GAAMAPTTDP1HTTMEN1 | |
| SCHEMBL691717 | 0.82 | MDM2 (0.37) | LMNA | |
| SCHEMBL29697836 | 0.82 | DPP4 (0.45) | LMNAGAAMAPTTDP1ALDH1A1 | |
| SCHEMBL691094 | 0.79 | SIGMAR1 (0.43) | GAAMAPTALDH1A1HTTMEN1 | |
| SCHEMBL691883 | 0.78 | HTR2C (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3626167 | 0.77 | BRD4 (0.39) | GAAALDH1A1KMT2A | |
| SCHEMBL3630035 | 0.77 | BRD4 (0.39) | GAAALDH1A1KMT2A | |
| SCHEMBL16819095 | 0.76 | TSHR (0.38) | MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010124042-A2 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-10-28 | — | — | WO | disclosed |