⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38438 | 0.72 | — | — | |
| SCHEMBL14010945 | 0.72 | — | — | |
| SCHEMBL550997 | 0.68 | — | — | |
| SCHEMBL6885496 | 0.68 | TSHR (0.31) | — | |
| SCHEMBL6843784 | 0.67 | ALDH1A1 (0.38) | — | |
| SCHEMBL1628830 | 0.67 | — | — | |
| Alcohol SCHEMBL1226116 | 0.67 | AKR1B1 (0.31) | — | |
| Vinyl Chloride SCHEMBL10468846 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL7777017 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL12216596 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975119-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2021-04-13 | — | — | US | disclosed |
| US-20180186833-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-07-05 | — | — | US | disclosed |
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |
| EP-2697246-B1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-03-07 | — | — | EP | disclosed |
| EP-2697246-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | Novagenesis Foundation (CH) | 2014-02-19 | — | — | EP | disclosed |
| US-20140038903-A1 | Selective Cysteine Protease Inhibitors and Uses Thereof | NEW WORLD LABORATORIES, INC. (CA) | 2014-02-06 | — | — | US | disclosed |
| WO-2012140500-A9 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES, INC. (CA) | 2013-10-24 | — | — | WO | disclosed |
| WO-2012140500-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES, INC. (CA) | 2012-10-18 | — | — | WO | disclosed |
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |