Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720275 | 0.88 | LMNA (0.32) | LMNASMN1; SMN2CYP1A2CYP2C19HIF1A | |
| SCHEMBL3720538 | 0.88 | LMNA (0.31) | LMNASMN1; SMN2CYP1A2CYP2C19HIF1A | |
| SCHEMBL3726169 | 0.85 | HPGD (0.34) | ACACBLMNASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL3720478 | 0.85 | GLA (0.40) | ACACBLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL3720633 | 0.84 | SMN1; SMN2 (0.33) | ACACBLMNASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL3724124 | 0.82 | MTNR1A (0.49) | ACACBLMNAHIF1AMAPTRXFP1 | |
| SCHEMBL3720459 | 0.82 | ACACB (0.38) | ACACB | |
| SCHEMBL3721014 | 0.80 | ACACB (0.41) | ACACB | |
| SCHEMBL3720162 | 0.80 | ALDH1A1 (0.31) | LMNASMN1; SMN2CYP1A2CYP2C19HTT | |
| SCHEMBL3719889 | 0.80 | PDE4B (0.42) | ACACBLMNASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |