Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.35 |
| ▸ | S100A10 | P60903 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720678 | 0.82 | HRH3 (0.41) | NOTUM | |
| SCHEMBL3725480 | 0.82 | EPHX2 (0.40) | KDM1ANOTUMKCNH2EPHX2 | |
| SCHEMBL1580970 | 0.81 | NOTUM (0.47) | NOTUMMAPK1MEN1KMT2A | |
| SCHEMBL1056139 | 0.78 | KDM1A (0.40) | KDM1ANOTUMEPHX2 | |
| SCHEMBL21381933 | 0.76 | KDM1A (0.49) | KDM1ANOTUMCHRM2DRD2CHRNB2 | |
| SCHEMBL3724286 | 0.76 | NOTUM (0.42) | NOTUMCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3729093 | 0.75 | F2R (0.39) | — | |
| SCHEMBL23932469 | 0.74 | AKR1C3 (0.57) | KAT2BMEN1KMT2A | |
| SCHEMBL23605292 | 0.72 | QDPR (0.51) | KDM1ACHRM2DRD2CHRNB2DRD4 | |
| SCHEMBL16649573 | 0.71 | KDM1A (0.66) | KDM1ACHRM2DRD2CHRNB2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136144-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |