Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.78 |
| ▸ | GAA | P10253 | 7/20 | 0.78 |
| ▸ | HPGD | P15428 | 7/20 | 0.78 |
| ▸ | GLA | P06280 | 6/20 | 0.78 |
| ▸ | CASP1 | P29466 | 5/20 | 0.78 |
| ▸ | CASP7 | P55210 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.78 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.78 |
| ▸ | ALPG | P10696 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | GFER | P55789 | 1/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266846 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL6269572 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7454040 | 0.83 | KDM4E (0.78) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL8807762 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| 4-Methylesculetin SCHEMBL6839210 | 0.80 | MCL1 (0.96) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL2417272 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7299491 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL6262436 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| 4-Methylesculetin SCHEMBL409482 | 0.78 | MCL1 (1.00) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| 4-Methylesculetin SCHEMBL29361762 | 0.78 | MCL1 (1.00) | KDM4EALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100112100-A1 | COMPOSITIONS COMPRISING A C-GLYCOSIDE COMPOUND | L'OREAL (FR) | 2010-05-06 | — | — | US | disclosed |
| US-20080226756-A1 | COMPOSITIONS COMPRISING A C-GLYCOSIDE COMPOUND | L'OREAL (FR) | 2008-09-18 | — | — | US | disclosed |
| US-20060069032-A1 | Beta-endorphin activity in cosmetics and dermatology | L'OREAL (FR) | 2006-03-30 | — | — | US | disclosed |
| US-20050036974-A1 | Beta-endorphin activity in cosmetics and dermatology | L'OREAL (FR) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080226756-A1 | COMPOSITIONS COMPRISING A C-GLYCOSIDE COMPOUND | UGCG, GANC, CUTA | KDM4E 1043/4885ALDH1A1 3083/4885HSD17B10 1120/4885 |
| US-20100112100-A1 | COMPOSITIONS COMPRISING A C-GLYCOSIDE COMPOUND | UGCG, GANC, CUTA | KDM4E 1043/4885ALDH1A1 3083/4885HSD17B10 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.