Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.78 |
| ▸ | GAA | P10253 | 8/20 | 0.78 |
| ▸ | GLA | P06280 | 7/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.78 |
| ▸ | HPGD | P15428 | 6/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | CASP1 | P29466 | 4/20 | 0.78 |
| ▸ | CASP7 | P55210 | 4/20 | 0.78 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.78 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.78 |
| ▸ | ALPG | P10696 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | GFER | P55789 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266846 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1GAAGLAHSD17B10 | |
| SCHEMBL7452974 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1GAAGLAHSD17B10 | |
| SCHEMBL3724696 | 0.83 | KDM4E (0.78) | KDM4EALDH1A1GAAGLAHSD17B10 | |
| SCHEMBL7460975 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1GAAGLAHSD17B10 | |
| SCHEMBL13609429 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1GAAGLAHSD17B10 | |
| SCHEMBL12055355 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1GAAGLAHSD17B10 | |
| SCHEMBL580501 | 0.75 | ALDH1A1 (0.74) | KDM4EALDH1A1GAAGLAHSD17B10 | |
| SCHEMBL335474 | 0.74 | KDM4E (1.00) | KDM4EALDH1A1GAAGLAHSD17B10 | |
| SCHEMBL29651337 | 0.74 | KDM4E (1.00) | KDM4EALDH1A1GAAGLAHSD17B10 | |
| SCHEMBL6268138 | 0.72 | KDM4E (0.71) | KDM4EALDH1A1GAAGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254955-A1 | A method for regulating gene expression | RIKEN (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-6472541-B2 | HALOGENATED- COUMARIN, QUINOLINE-2-ONE, XANTHENE, THIOXANTHENE, SELENOXANTHENEN, OR ANTHRACENE DERIVATIVES; IRRADIATING TO CONTROL THE RELEASE OF THE SOMPOUND SPATIALLY AND TEMPORALLY TO PROBE ITS BIOLOGICAL EFFECTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-10-29 | — | — | US | disclosed |
| US-20020155606-A1 | Regulating gene expression in preferential cells; obtain cells, incubate with disruptive agent and expose to ultraviolet radiation, monitor gene expression | RIKEN (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1151350-A4 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | UNIV CALIFORNIA (US) | 2002-08-21 | — | — | EP | disclosed |
| US-20020016472-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2002-02-07 | — | — | US | disclosed |
| EP-1151350-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | The Regents of the University of California (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000031588-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020155606-A1 | Regulating gene expression in preferential cells; obtain cells, incubate with disruptive agent and expose to ultraviolet radiation, monitor gene expression | ERCC2, DCLRE1B, DDB1 | KDM4E 3853/4885ALDH1A1 2243/4885GAA 1272/4885 |
| US-20020016472-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | ERCC4, XPA, GPX4 | KDM4E 4063/4885ALDH1A1 748/4885GAA 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.