SCHEMBL372471

SCHEMBL372471

Cc1ccc(OB(O)Oc2ccccc2O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
TP53 P04637 2/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
GAA P10253 3/20 0.41
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
LMNA P02545 4/20 0.37
PNLIP P16233 1/20 0.37
MAPT P10636 4/20 0.36
JAK2 O60674 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
NPC1 O15118 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HTR2A P28223 2/20 0.35
SLC6A4 P31645 2/20 0.35
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7065793 0.85 CA2 (0.43) TSHRTP53CA1CA2GAA
SCHEMBL8469357 0.83 CA2 (0.52) TSHRTP53CA1CA2GAA
SCHEMBL2413438 0.81 HTT (0.44) TSHRCA1CA2LMNAMEN1
SCHEMBL10632841 0.81 ACHE (0.48) TSHRCA1CA2LMNAMAPT
SCHEMBL3179793 0.76 LMNA (0.54) TSHRTP53CA1CA2GAA
SCHEMBL30975118 0.76 LMNA (0.54) TSHRTP53CA1CA2GAA
SCHEMBL28577432 0.74 CA1 (0.39) TSHRTP53CA1CA2GAA
SCHEMBL29817527 0.71 LMNA (0.50) TSHRTP53CA1CA2GAA
SCHEMBL29790333 0.71 CA2 (0.52) TSHRTP53CA1CA2GAA
SCHEMBL862053 0.71 CA2 (0.52) TSHRTP53CA1CA2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3330314-B1 POLYETHYLENE COMPOSITION INEOS EUROPE AG (CH) 2024-05-01 EP disclosed
EP-4321564-A2 COPOLYMERS AND FILMS THEREOF Ineos Europe AG (CH) 2024-02-14 EP disclosed
EP-3320003-B1 COPOLYMERS AND FILMS THEREOF INEOS EUROPE AG (CH) 2024-01-10 EP disclosed
EP-2880067-B2 PIPES INEOS EUROPE AG (CH) 2021-09-15 EP disclosed
EP-3092180-B1 POLYMER COMPOSITION FOR CAPS AND CLOSURES INEOS EUROPE AG (CH) 2020-07-22 EP disclosed
US-10676550-B2 Copolymers and films thereof INEOS EUROPE AG (CH) 2020-06-09 US disclosed
EP-1891122-B1 SUPPORTED POLYMERISATION CATALYSTS INEOS SALES UK LTD (GB) 2020-03-25 EP disclosed
US-10364309-B2 Supported polymerisation catalysts INEOS SALES (UK) LIMITED (GB) 2019-07-30 US disclosed
EP-2242877-B1 FIBRES, TAPES, MONOFILAMENTS BASED ON ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS INEOS MFG BELGIUM NV (BE) 2019-07-03 EP disclosed
EP-2880067-B1 PIPES INEOS EUROPE AG (CH) 2019-01-02 EP disclosed
WO-2006131703-A2 SUPPORTED POLYMERISATION CATALYSTS INEOS EUROPE LIMITED (GB) 2006-12-14 WO disclosed
EP-1731536-A1 Supported polymerisation catalysts Innovene Manufacturing France SAS (FR) 2006-12-13 EP disclosed
EP-1731537-A1 Supported polymerisation catalysts Innovene Manufacturing France SAS (FR) 2006-12-13 EP disclosed
EP-1693388-A1 Polymerisation catalysts INNOVENE EUROPE LIMITED (GB) 2006-08-23 EP disclosed
US-20060100402-A1 Supported olefin polymerization catalyst INEOS COMMERCIAL SERVICES UK LIMITED (GB) 2006-05-11 US disclosed
US-20050255988-A1 Supported polymerisation catalysts BARCLAYS BANK PLC (GB) 2005-11-17 US disclosed
US-20050245699-A1 Olefin polymerisation process INEOS COMMERCIAL SERVICES UK LIMITED (GB) 2005-11-03 US disclosed
EP-1567564-A1 SUPPORTED POLYMERISATION CATALYSTS Innovene Europe Limited (GB) 2005-08-31 EP disclosed
WO-2004018531-A1 SUPPORTED POLYMERISATION CATALYSTS BP CHEMICALS LIMITED (GB) 2004-03-04 WO disclosed
WO-2000014129-A1 LONG CHAIN BRANCHED ETHYLENE HOMOPOLYMER MADE BY A SLURRY PROCESS AND BLENDS THEREOF THE DOW CHEMICAL COMPANY (US) 2000-03-16 WO disclosed