SCHEMBL3724951

SCHEMBL3724951

CCCc1ccccc1-c1c2ccccc2c(-c2ccccc2CCC)c2c(OC)c3ccccc3c(OC)c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPK1 P28482 1/20 0.42
POLB P06746 1/20 0.36
ELANE P08246 1/20 0.35
PKM P14618 1/20 0.34
GAA P10253 2/20 0.34
HPGD P15428 1/20 0.34
GPR84 Q9NQS5 1/20 0.34
PPARA Q07869 1/20 0.33
MCL1 Q07820 1/20 0.33
FPR1 P21462 1/20 0.32
CYP2C9 P11712 1/20 0.32
CTSL P07711 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ADRA2A P08913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3725216 0.91 KDM4E (0.40) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL3728184 0.87 KDM4E (0.45) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL3720664 0.85 KDM4E (0.37) KDM4EALDH1A1ELANEGAAHPGD
SCHEMBL3731388 0.75 ALDH1A1 (0.50) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL3725184 0.75 LIPG (0.41) KDM4EELANECYP2C9
SCHEMBL28193344 0.72 ALDH1A1 (0.58) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL6704515 0.71 PPARA (0.41) KDM4EALDH1A1ELANEGAAHPGD
SCHEMBL9170451 0.70 SLC2A1 (0.45) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL3721505 0.70 CYP2D6 (0.39) ALDH1A1SMN1; SMN2MAPK1HPGDMEN1
SCHEMBL27664396 0.70 KDM4E (0.48) KDM4EALDH1A1SMN1; SMN2MAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070141747-A1 Electronic device fabrication process XEROX CORPORATION 2007-06-21 US claimed
US-7651885-B2 Electronic device fabrication process XEROX CORPORATION (US) 2010-01-26 US disclosed
US-20070141747-A1 Electronic device fabrication process XEROX CORPORATION 2007-06-21 US disclosed