Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577982 | 0.71 | CCR4 (0.33) | CCR4DHODHTYK2 | |
| SCHEMBL2838403 | 0.70 | METAP1 (0.44) | CCR4MAPTRAB9AL3MBTL1CYP1A2 | |
| SCHEMBL13996109 | 0.69 | ALDH1A1 (0.54) | CCR4TYK2MAPTRAB9AL3MBTL1 | |
| SCHEMBL577313 | 0.68 | CCR4 (0.39) | CCR4TYK2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL62767 | 0.67 | SREBF2 (0.50) | CCR4MAPTRAB9AL3MBTL1 | |
| SCHEMBL15640643 | 0.66 | TYK2 (0.41) | CCR4TYK2MAPTL3MBTL1CYP1A2 | |
| SCHEMBL2861979 | 0.66 | CCR4 (0.41) | CCR4MAPTRAB9ACYP1A2CYP2D6 | |
| SCHEMBL577645 | 0.66 | CCR4 (0.38) | CCR4TYK2MAPTRAB9APAX8 | |
| SCHEMBL577312 | 0.66 | CCR4 (0.39) | CCR4TYK2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL576843 | 0.65 | CCR4 (0.38) | CCR4TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118078-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | claimed |