SCHEMBL3725404

SCHEMBL3725404

CCN(C=O)CC.O=CN(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
TSHR P16473 3/20 0.42
GLA P06280 1/20 0.42
TP53 P04637 2/20 0.38
KMT2A Q03164 5/20 0.36
MEN1 O00255 3/20 0.36
ALDH3A1 P30838 1/20 0.35
ALDH1A3 P47895 1/20 0.35
CYP2A6 P11509 1/20 0.34
HTT P42858 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
NPC1 O15118 2/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34
ESR1 P03372 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NR3C2 P08235 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5516786 0.82 ALDH1A1 (0.42) ALDH1A1TSHRGLAKMT2AMEN1
SCHEMBL43388 0.82 ALDH1A1 (0.42) ALDH1A1TSHRGLAKMT2AMEN1
Toluene SCHEMBL11194057 0.79 LMNA (0.48) ALDH1A1TSHRGLAKMT2AMEN1
Aniline SCHEMBL10692374 0.78 TSHR (0.46) ALDH1A1TSHRGLAKMT2AMEN1
SCHEMBL7757804 0.76 ALDH1A1 (0.34) ALDH1A1TSHRGLATP53KMT2A
SCHEMBL14479530 0.76 TSHR (0.47) ALDH1A1TSHRGLATP53KMT2A
SCHEMBL172583 0.75 CA12 (0.44) ALDH1A1TSHRKMT2AMEN1CYP2A6
SCHEMBL28869065 0.75 TSHR (0.42) ALDH1A1TSHRKMT2AMEN1CYP2A6
SCHEMBL31116625 0.74 TSHR (0.48) ALDH1A1TSHRGLATP53KMT2A
SCHEMBL305842 0.74 TSHR (0.48) ALDH1A1TSHRGLATP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7674438-B2 Systems of producing monoolefins by the extraction-hydrogenation of highly unsaturated hydrocarbons CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-03-09 US claimed
US-20070149835-A1 SYSTEMS OF PRODUCING MONOOLEFINS BY THE EXTRACTION-HYDROGENATION OF HIGHLY UNSATURATED HYDROCARBONS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-06-28 US claimed
WO-2005049533-A1 METHODS AND SYSTEMS OF PRODUCING MONOOLEFINS BY THE EXTRACTION-HYDROGENATION OF HIGHLY UNSATURATED HYDROCARBONS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2005-06-02 WO claimed
US-20050107649-A1 Methods and systems of producing monoolefins by the extraction-hydrogenation of highly unsaturated hydrocarbons CHEVRON PHILLIPS CHEMICAL COMPANY LP 2005-05-19 US claimed