SCHEMBL7757804

SCHEMBL7757804

CCN(C=O)CC.c1ccc([Bi](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.34
CYP2A6 P11509 1/20 0.34
TSHR P16473 2/20 0.34
GLA P06280 1/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 3/20 0.32
MAPT P10636 2/20 0.32
ALDH3A1 P30838 1/20 0.31
ALDH1A3 P47895 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 2/20 0.31
PGR P06401 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL11194057 0.79 LMNA (0.48) ALDH1A1CYP2A6TSHRGLANPSR1
Aniline SCHEMBL10692374 0.78 TSHR (0.46) ALDH1A1CYP2A6TSHRGLANPSR1
SCHEMBL3725404 0.76 ALDH1A1 (0.42) ALDH1A1CYP2A6TSHRGLANPSR1
SCHEMBL968495 0.73 LMNA (0.48) ALDH1A1TSHRNPC1LMNATP53
SCHEMBL11676648 0.73 LMNA (0.49) ALDH1A1NPSR1MEN1KMT2AL3MBTL1
Diphenylmethanol SCHEMBL8527825 0.73 LMNA (0.44) ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL27084 0.72
SCHEMBL5518857 0.72
SCHEMBL27668697 0.72 ALDH1A1 (0.38) ALDH1A1TSHRALDH3A1ALDH1A3
SCHEMBL7397101 0.71 AOC3 (0.53) MEN1KMT2ANPC1ADRA2AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5730953-A RADIOGRAPHIC CONTRAST MEDIUM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 US claimed
EP-0716091-B1 TRIS(SUBSTITUTED PHENYL)BISMUTH DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2001-03-21 EP disclosed
US-5730953-A RADIOGRAPHIC CONTRAST MEDIUM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
EP-0716091-A1 TRIS(SUBSTITUTED PHENYL)BISMUTH DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-06-12 EP disclosed