SCHEMBL372558

SCHEMBL372558

COC(OC)c1cnc2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.52
KDM4E B2RXH2 3/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
PDGFRB P09619 3/20 0.46
PDGFRA P16234 3/20 0.46
MGAM O43451 1/20 0.42
PDE4D Q08499 2/20 0.42
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
ALDH1A1 P00352 2/20 0.41
RAB9A P51151 1/20 0.41
HTR3A P46098 1/20 0.41
CYP2A6 P11509 1/20 0.40
NQO1 P15559 1/20 0.40
BIRC5 O15392 1/20 0.39
GLA P06280 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2607479 0.79 CYP1A2 (0.57) CYP1A2KDM4EPDGFRBPDGFRAMGAM
SCHEMBL26750740 0.79 ALDH1A1 (0.43) CYP1A2KMT2APDGFRBPDGFRAALDH1A1
SCHEMBL15668192 0.78 PDE10A (0.41) KMT2APDGFRBPDGFRAALDH1A1GLA
SCHEMBL20030180 0.78 CYP1A2 (0.44) CYP1A2KDM4EKMT2ASMN1; SMN2PDGFRB
SCHEMBL23773965 0.76 CYP1A2 (0.53) CYP1A2KDM4EPDGFRBPDGFRAMGAM
SCHEMBL1253863 0.76 CYP1A2 (0.53) CYP1A2KDM4EPDGFRBPDGFRAMGAM
SCHEMBL23847796 0.76 CYP1A2 (0.53) CYP1A2KDM4EPDGFRBPDGFRAMGAM
SCHEMBL28467592 0.76 CYP1A2 (0.53) CYP1A2KDM4EPDGFRBPDGFRAMGAM
SCHEMBL25085747 0.76 CYP1A2 (0.53) CYP1A2KDM4EPDGFRBPDGFRAMGAM
SCHEMBL20023742 0.76 CYP1A2 (0.53) CYP1A2KDM4EPDGFRBPDGFRAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4519384-B1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORP (US) 2026-04-29 EP disclosed
EP-4519384-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF Promega Corporation (US) 2025-03-12 EP disclosed
EP-4519385-A2 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION (US) 2025-03-12 EP disclosed
US-20240191211-A1 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION 2024-06-13 US disclosed
WO-2023215497-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION (US) 2023-11-09 WO disclosed
US-20230357266-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION 2023-11-09 US disclosed
WO-2023215514-A2 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION (US) 2023-11-09 WO disclosed
WO-2023215514-A2 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION (US) 2023-11-09 WO disclosed
US-20230357266-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION 2023-11-09 US disclosed
US-20230357266-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION 2023-11-09 US disclosed
CN-1663952-A Preparation of quinoline-substituted carbonate and carbamate derivatives ABBOTT LAB (US) 2005-09-07 CN disclosed
CN-1217934-C Process for the preparation of quinoline-substituted carbonate and carbamate derivatives ABBOTT LAB (US) 2005-09-07 CN disclosed
US-20030199696-A1 Preparation of quinoline-substituted carbonate and carbamate derivatives ABBVIE INC. 2003-10-23 US disclosed
US-6579986-B2 Metal-catalyzed coupling reactions for 6-o-substituted macrolide antibiotics ABBOTT LABORATORIES 2003-06-17 US disclosed
US-20020165390-A1 Preparation of quinoline-substituted carbonate and carbamate derivatives ABBVIE INC. 2002-11-07 US disclosed
CN-1370148-A Process for the preparation of quinoline-substituted carbonate and carbamate derivatives ABBOTT LAB (US) 2002-09-18 CN disclosed
US-6417366-B2 CHEMICAL INTERMEDIATE FOR MACROLACTONE ANTIBIOTIC ABBOTT LABORATORIES 2002-07-09 US disclosed
EP-1192139-A1 PREPARATION OF QUINOLINE-SUBSTITUTED CARBONATE AND CARBAMATE DERIVATIVES Abbott Laboratories (US) 2002-04-03 EP disclosed
US-20020013468-A1 Preparation of quinoline-substituted carbonate and carbamate derivatives ABBVIE INC. 2002-01-31 US disclosed
WO-2001000582-A1 PREPARATION OF QUINOLINE-SUBSTITUTED CARBONATE AND CARBAMATE DERIVATIVES ABBOTT LABORATORIES (US) 2001-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357266-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF BTD, HLCS, TYR CYP1A2 971/4885KDM4E 1476/4885KMT2A 2293/4885
US-20030199696-A1 Preparation of quinoline-substituted carbonate and carbamate derivatives CA7, CA6, CA4 CYP1A2 47/4885KDM4E 211/4885KMT2A 567/4885
US-20020165390-A1 Preparation of quinoline-substituted carbonate and carbamate derivatives CA7, CA6, CA4 CYP1A2 47/4885KDM4E 211/4885KMT2A 567/4885
US-20020013468-A1 Preparation of quinoline-substituted carbonate and carbamate derivatives CA7, CA6, CA4 CYP1A2 47/4885KDM4E 211/4885KMT2A 567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.