SCHEMBL372743

SCHEMBL372743

CCCCO[Si](NCC)(OCCCC)OCCCC

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
TSHR P16473 4/20 0.35
LMNA P02545 1/20 0.35
ATM Q13315 1/20 0.33
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6235362 0.87 EPHX1 (0.31)
SCHEMBL372997 0.84
SCHEMBL372565 0.83 TSHR (0.35) ADRB2ADRB1ADRB3TSHRLMNA
SCHEMBL372467 0.83 ADRB2 (0.35) ADRB2ADRB1ADRB3TSHRLMNA
SCHEMBL373024 0.81 TSHR (0.40) ADRB2ADRB1ADRB3TSHRLMNA
SCHEMBL372234 0.79 EPHX1 (0.41) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL372567 0.79 EPHX1 (0.41) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL372817 0.79 EPHX1 (0.41) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL495520 0.78
SCHEMBL938350 0.78 ADRB2 (0.31) ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11465570-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2022-10-11 US claimed
US-20200198555-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-06-25 US claimed
US-10632936-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-04-28 US claimed
US-20180326922-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2018-11-15 US claimed
US-9133281-B2 Preparation and use of functionalized elastomers in rubber compositions containing silica filler and tire components thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-09-15 US claimed
US-20140155542-A1 PREPARATION AND USE OF FUNCTIONALIZED ELASTOMERS IN RUBBER COMPOSITIONS CONTAINING SILICA FILLER AND TIRE COMPONENTS THEREOF THE GOODYEAR TIRE & RUBBER COMPANY (US) 2014-06-05 US claimed
US-8357747-B2 Polymer compositions comprising fluoro elastomers and expanded perlite IMERYS FILTRATION MINERALS, INC. (US) 2013-01-22 US claimed
EP-2410025-A1 Barrier compositions Imerys Minerals Limited (GB) 2012-01-25 EP claimed
US-20100317789-A1 Polymer Compositions Comprising Fluoro Elastomers and Expanded Perlite WORLD MINERALS, INC 2010-12-16 US claimed
US-20100105824-A1 Polymer Compositions WORLD MINERALS, INC. (US) 2010-04-29 US claimed
US-20090321681-A1 Barrier Compositions IMERYS MINERALS, LTD. (GB) 2009-12-31 US claimed
EP-2115057-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE World Minerals, Inc. (US) 2009-11-11 EP claimed
EP-2016139-A2 BARRIER COMPOSITIONS Imerys Minerals Limited (GB) 2009-01-21 EP claimed
WO-2008081173-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE WORLD MINERALS, INC. (US) 2008-07-10 WO claimed
WO-2008053236-A1 POLYMER COMPOSITIONS WORLD MINERALS, INC. (US) 2008-05-08 WO claimed
WO-2007125312-A2 BARRIER COMPOSITIONS IMERYS MINERALS LIMITED (GB) 2007-11-08 WO claimed
EP-1809581-A1 PARTICULATE MATERIAL Imerys Minerals Limited (GB) 2007-07-25 EP claimed
WO-2007010276-A1 PARTICULATE MATERIAL IMERYS MINERALS LIMITED (GB) 2007-01-25 WO claimed
EP-4150010-B1 TALC PARTICULATE IMERTECH SAS (FR) 2026-02-25 EP disclosed
US-5698619-A Aminosilane compounds in silica-filled rubber compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-12-16 US disclosed