Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 14/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719152 | 0.82 | AR (0.48) | SLC22A12ARCTSSCTSKPGR | |
| SCHEMBL3730195 | 0.82 | AR (0.48) | SLC22A12ARCTSSPGR | |
| SCHEMBL3722067 | 0.79 | MAPK10 (0.42) | MAPK8MAPK10MAPTRAB9A | |
| SCHEMBL672513 | 0.77 | SRC (0.40) | ARMAPK8MAPK10PGRNPC1 | |
| SCHEMBL1006358 | 0.76 | MAPT (0.46) | SLC22A12NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL756605 | 0.76 | AR (0.52) | ARPGRRAB9A | |
| SCHEMBL3725849 | 0.76 | AR (0.44) | ARMAPK8MAPK10CTSSPGR | |
| SCHEMBL24424820 | 0.75 | AR (0.44) | ARCTSSCTSKPGRMAPT | |
| Trifluoroacetic Acid SCHEMBL3720595 | 0.73 | MAPK10 (0.44) | MAPK8MAPK10LMNA | |
| SCHEMBL15096357 | 0.73 | AR (0.60) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |