Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730195 | 0.86 | AR (0.48) | ARPGRCTSS | |
| SCHEMBL3719152 | 0.81 | AR (0.48) | ARPGRCTSS | |
| SCHEMBL756605 | 0.77 | AR (0.52) | ARPGR | |
| SCHEMBL3725903 | 0.76 | SLC22A12 (0.45) | ARPGRMAPK10MAPK8CTSS | |
| SCHEMBL15832067 | 0.73 | AR (0.54) | ARPGR | |
| SCHEMBL15832056 | 0.73 | AR (0.61) | ARPGR | |
| Trifluoroacetic Acid SCHEMBL3722062 | 0.72 | MAPK10 (0.44) | MAPK10MAPK8 | |
| SCHEMBL29775318 | 0.72 | CA12 (0.56) | ARPGR | |
| SCHEMBL12422332 | 0.72 | CA12 (0.56) | ARPGR | |
| SCHEMBL8116738 | 0.71 | L3MBTL1 (0.47) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |