Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730195 | 0.87 | AR (0.48) | ARPGRCTSSSLC22A12 | |
| SCHEMBL3725903 | 0.82 | SLC22A12 (0.45) | ARPGRCTSSCTSKSLC22A12 | |
| SCHEMBL756605 | 0.81 | AR (0.52) | ARPGR | |
| SCHEMBL3725849 | 0.81 | AR (0.44) | ARPGRCTSS | |
| SCHEMBL4050631 | 0.80 | AR (0.47) | ARPGR | |
| SCHEMBL3722003 | 0.80 | SLC22A12 (0.46) | ARSLC22A12 | |
| SCHEMBL3721302 | 0.79 | AR (0.44) | ARCTSKSLC22A12 | |
| SCHEMBL3722872 | 0.79 | L3MBTL1 (0.41) | AR | |
| SCHEMBL3722058 | 0.78 | L3MBTL1 (0.40) | AR | |
| SCHEMBL3719026 | 0.78 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |