Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.66 |
| ▸ | ALB | P02768 | 8/20 | 0.55 |
| ▸ | IL2 | P60568 | 8/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PCNA | P12004 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725913 | 1.00 | FOLH1 (0.66) | FOLH1ALBIL2TNFLMNA | |
| SCHEMBL468853 | 0.96 | FOLH1 (0.70) | FOLH1ALBIL2TNFLMNA | |
| SCHEMBL468855 | 0.96 | FOLH1 (0.70) | FOLH1ALBIL2TNFLMNA | |
| SCHEMBL468886 | 0.90 | SIRT5 (0.52) | FOLH1ALBIL2LMNATHRB | |
| SCHEMBL468888 | 0.90 | SIRT5 (0.52) | FOLH1ALBIL2LMNATHRB | |
| SCHEMBL8200137 | 0.89 | FOLH1 (0.59) | FOLH1ALBIL2TNFLMNA | |
| SCHEMBL9787629 | 0.83 | MME (0.60) | FOLH1LMNAPPARGMEN1KMT2A | |
| SCHEMBL29367167 | 0.83 | MME (0.60) | FOLH1LMNAPPARGMEN1KMT2A | |
| SCHEMBL468823 | 0.83 | MME (0.60) | FOLH1LMNAPPARGMEN1KMT2A | |
| SCHEMBL328475 | 0.83 | MME (0.60) | FOLH1LMNAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41278-E1 | N-acetyl aldosamines and related N-acetyl compounds, and their topical use | TRISTRATA, INC. | 2010-04-27 | — | — | US | claimed |
| US-6524593-B1 | Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails | TRISTRATA, INC. | 2003-02-25 | — | — | US | claimed |