Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30110793 | 0.68 | ADAMTS4 (0.31) | ALDH1A1CA2LMNAHSD17B10CA1 | |
| Resorcinol SCHEMBL4643516 | 0.67 | CA12 (0.86) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL15515 | 0.67 | — | — | |
| Resorcinol SCHEMBL326229 | 0.67 | CA12 (1.00) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL3799798 | 0.65 | ALDH1A1 (0.80) | ALDH1A1CA12CA2CA9CYP3A4 | |
| SCHEMBL4819249 | 0.65 | — | — | |
| Resorcinol SCHEMBL11679916 | 0.64 | CA12 (0.92) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL8829963 | 0.64 | — | — | |
| Resorcinol SCHEMBL20577903 | 0.64 | — | — | |
| Resorcinol SCHEMBL563023 | 0.64 | CA12 (0.92) | ALDH1A1CA12CA2CA9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010134082-A1 | CHROMENONE DERIVATIVES FOR TREATMENT OF CANCER | PROTEOLOGICS LTD (IL) | 2010-11-25 | — | — | WO | disclosed |