Resorcinol

Resorcinol

SCHEMBL4643516

Oc1cccc(O)c1.[Na+].[OH-]

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Resorcinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 4/20 0.86
CA2 known ✓ P00918 4/20 0.86
CA1 known ✓ P00915 3/20 0.55
CA4 known ✓ P22748 1/20 0.47
CA9 Q16790 4/20 0.86
ALDH1A1 P00352 3/20 0.86
CA14 Q9ULX7 3/20 0.86
CYP3A4 P08684 3/20 0.86
LMNA P02545 1/20 0.86
CA5A P35218 1/20 0.86
HSD17B10 Q99714 1/20 0.86
CA5B Q9Y2D0 1/20 0.86
HSD17B1 P14061 4/20 0.55
HSD17B2 P37059 4/20 0.55
TSHR P16473 3/20 0.55
ACHE P22303 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
CYP2C9 P11712 1/20 0.55
CA7 P43166 1/20 0.55
LCK P06239 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resorcinol SCHEMBL15515 0.93
Resorcinol SCHEMBL326229 0.93 CA12 (1.00) CA12CA2CA9ALDH1A1CA14
Resorcinol SCHEMBL28838206 0.91 ALDH1A1 (0.71) CA12CA2CA9ALDH1A1CA14
Resorcinol SCHEMBL8442393 0.89
Resorcinol SCHEMBL5867187 0.89
Resorcinol SCHEMBL3984288 0.89 CA12 (0.92) CA12CA2CA9ALDH1A1CA14
Resorcinol SCHEMBL11679916 0.89 CA12 (0.92) CA12CA2CA9ALDH1A1CA14
Resorcinol SCHEMBL971994 0.89
Resorcinol SCHEMBL20577903 0.89
Resorcinol SCHEMBL8829963 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105938102-A Method for rapid determination of pesticide residues in fruits and vegetables through chemical developing method 四川理工学院 2016-09-14 CN claimed
CN-109645603-A A kind of antibacterial thermal insulating polyurethane composite material and its preparation process 广州甚多服装有限公司 2019-04-19 CN disclosed
CN-105938102-A Method for rapid determination of pesticide residues in fruits and vegetables through chemical developing method 四川理工学院 2016-09-14 CN disclosed
CN-105818292-A Preparation method of aramid composite 浙江恒泽环境科技有限公司 2016-08-03 CN disclosed
EP-1971646-A1 POLYARYLATE COMPOSITIONS USEFUL AS COATINGS , THEIR PREPARATION, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-09-24 EP disclosed
EP-1957558-A2 POLYARYLATE ACID CHLORIDE COMPOSITIONS AND DERIVATES THEREFROM General Electric Company (US) 2008-08-20 EP disclosed
WO-2007070377-A2 POLYARYLATE ACID CHLORIDE COMPOSITIONS AND DERIVATES THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-06-21 WO disclosed
US-20070135610-A1 Polyarylate acid chloride compositions and derivatives therefrom GENERAL ELECTRIC COMPANY (US) 2007-06-14 US disclosed
WO-2007067247-A1 POLYARYLATE COMPOSITIONS USEFUL AS COATINGS , THEIR PREPARATION, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-06-14 WO disclosed
US-20060093826-A1 Compositions useful as coatings, their preparation, and articles made therefrom GENERAL ELECTRIC COMPANY (US) 2006-05-04 US disclosed