Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593074 | 0.87 | TSHR (0.60) | FBP1TSHRCTSDALDH1A1TDP1 | |
| SCHEMBL299878 | 0.84 | FBP1 (0.49) | FBP1TSHRCTSDALDH1A1TDP1 | |
| SCHEMBL28149001 | 0.83 | CTSD (0.69) | FBP1TSHRCTSDALDH1A1TDP1 | |
| SCHEMBL10477073 | 0.81 | ALDH1A1 (0.53) | FBP1TSHRCTSDALDH1A1TDP1 | |
| SCHEMBL103644 | 0.81 | CTSD (0.65) | TSHRCTSDALDH1A1TDP1CYP1A2 | |
| SCHEMBL28221727 | 0.80 | TDP1 (0.63) | FBP1TSHRALDH1A1TDP1CRHBP | |
| SCHEMBL10718417 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL16719902 | 0.80 | TSHR (0.53) | FBP1TSHRCTSDALDH1A1TDP1 | |
| SCHEMBL16120074 | 0.80 | SLC6A2 (0.58) | FBP1TSHRCTSDALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10567555 | 0.79 | CTSD (0.62) | TSHRCTSDALDH1A1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120987-A1 | RING FUSED, UREIDOARYL- AND CARBAMOYLARYL-BRIDGED MORPHOLINO-PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH LLC (US) | 2010-10-21 | — | — | WO | disclosed |