Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960517 | 0.85 | TSHR (0.44) | L3MBTL1TDP1NAAATSHRHRH4 | |
| SCHEMBL1742833 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TDP1NAAATSHRHRH4 | |
| SCHEMBL2560206 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TDP1NAAATSHRHRH4 | |
| SCHEMBL1743547 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TDP1NAAATSHRHRH4 | |
| SCHEMBL29132544 | 0.82 | L3MBTL1 (0.41) | L3MBTL1TDP1NAAATSHRHRH4 | |
| SCHEMBL30378547 | 0.82 | L3MBTL1 (0.41) | L3MBTL1TDP1NAAATSHRHRH4 | |
| SCHEMBL13986786 | 0.79 | L3MBTL1 (0.39) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL16829804 | 0.78 | L3MBTL1 (0.38) | L3MBTL1TDP1NAAATSHRHRH4 | |
| SCHEMBL6598244 | 0.77 | L3MBTL1 (0.37) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL1337859 | 0.77 | SIGMAR1 (0.40) | L3MBTL1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135424-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-11-25 | — | — | WO | disclosed |