Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 2/20 | 0.59 |
| ▸ | PEPD | P12955 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | KIF11 | P52732 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645413 | 0.84 | KMT2A (0.75) | ALDH1A1GLAHSD17B10MEN1KMT2A | |
| SCHEMBL8264218 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GLAPEPDHSD17B10NPC1 | |
| SCHEMBL5062623 | 0.82 | PEPD (0.80) | ALDH1A1GLAPEPDHSD17B10NPC1 | |
| SCHEMBL6284986 | 0.82 | KMT2A (0.64) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL28804310 | 0.81 | ALDH1A1 (0.53) | ALDH1A1GLAPEPDHSD17B10NPC1 | |
| SCHEMBL8264226 | 0.80 | ALDH1A1 (0.56) | ALDH1A1GLAPEPDHSD17B10NPC1 | |
| SCHEMBL360387 | 0.79 | NPC1 (0.70) | ALDH1A1GLAPEPDHSD17B10NPC1 | |
| SCHEMBL17236529 | 0.78 | RXFP1 (0.54) | ALDH1A1GLAHSD17B10NPC1MEN1 | |
| SCHEMBL10708813 | 0.78 | GAA (0.55) | ALDH1A1GLANPC1MEN1KMT2A | |
| SCHEMBL2142002 | 0.77 | ALDH1A1 (0.70) | ALDH1A1GLAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120994-A2 | UREIDOARYL-AND CARBAMOYLARYL-MORPHOLINO- PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESIS | WYETH LLC (US) | 2010-10-21 | — | — | WO | disclosed |
| US-4507445-A | Heat-curable epoxide resin compositions | CIBA-GEIGY CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |