SCHEMBL28804310

SCHEMBL28804310

C=CC(=O)Oc1ccc(NC(N)=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
GLA P06280 2/20 0.53
HSD17B10 Q99714 1/20 0.50
PEPD P12955 1/20 0.50
TGM2 P21980 3/20 0.49
NPC1 O15118 1/20 0.48
THRB P10828 3/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 2/20 0.46
MAPT P10636 2/20 0.46
GFER P55789 2/20 0.46
KIF11 P52732 4/20 0.44
LMNA P02545 1/20 0.44
KDM4E B2RXH2 1/20 0.42
BLM P54132 1/20 0.42
CASP6 P55212 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7101252 0.82 KMT2A (0.70) ALDH1A1GLAHSD17B10TGM2THRB
SCHEMBL3726560 0.81 ALDH1A1 (0.59) ALDH1A1GLAHSD17B10PEPDNPC1
SCHEMBL10086611 0.81 THRB (0.53) ALDH1A1GLATGM2NPC1THRB
SCHEMBL2587522 0.80 THRB (0.64) ALDH1A1HSD17B10TGM2THRBMEN1
SCHEMBL28804343 0.80 KMT2A (0.46) ALDH1A1TGM2NPC1MEN1KMT2A
SCHEMBL21753720 0.79 SMN1; SMN2 (0.57) ALDH1A1TGM2NPC1KMT2AGAA
SCHEMBL30413748 0.79 ALDH1A1 (0.54) ALDH1A1GLAHSD17B10TGM2NPC1
SCHEMBL8264218 0.78 ALDH1A1 (0.61) ALDH1A1GLAHSD17B10PEPDNPC1
SCHEMBL28804186 0.77 MAPT (0.46) ALDH1A1GLAHSD17B10PEPDTGM2
SCHEMBL28527575 0.76 ALDH1A1 (0.63) ALDH1A1GLAHSD17B10PEPDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791361-B Positive lithographic printing plate precursor, method for producing same, and method for producing lithographic printing plate 富士胶片株式会社 2022-06-03 CN disclosed