⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1942581 | 1.00 | — | — | |
| SCHEMBL217913 | 0.96 | — | — | |
| SCHEMBL662260 | 0.89 | — | — | |
| SCHEMBL1515186 | 0.81 | — | — | |
| SCHEMBL4598920 | 0.80 | — | — | |
| SCHEMBL6607326 | 0.80 | CA2 (0.32) | — | |
| SCHEMBL6055461 | 0.78 | CA2 (0.31) | — | |
| SCHEMBL9647392 | 0.76 | — | — | |
| SCHEMBL900224 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL247765 | 0.69 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685575-A | Novel cooling substances and formulations containing these cooling substances | 西姆莱斯股份公司 | 2023-09-01 | — | — | CN | claimed |
| CN-110248939-B | Tyrosine amide derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2022-05-17 | — | — | CN | claimed |
| US-20210347780-A1 | CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO | Vyera Pharmaceuticals, LLC | 2021-11-11 | — | — | US | claimed |
| EP-3853230-A1 | CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO | Vyera Pharmaceuticals, LLC (US) | 2021-07-28 | — | — | EP | claimed |
| US-10954236-B2 | Tyrosine amide derivatives as Rho-Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2021-03-23 | — | — | US | claimed |
| EP-3573987-B1 | TYROSINE AMIDE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2021-03-10 | — | — | EP | claimed |
| WO-2020061279-A1 | CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO | Vyera Pharmaceuticals, LLC (US) | 2020-03-26 | — | — | WO | claimed |
| US-20200079774-A1 | TYROSINE AMIDE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2020-03-12 | — | — | US | claimed |
| EP-3080113-B1 | FUSED TRICYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB BIOPHARMA SPRL (BE) | 2019-09-18 | — | — | EP | claimed |
| EP-3363788-A1 | CANNABINOID RECEPTOR MODULATORS | Arena Pharmaceuticals, Inc. (US) | 2018-08-22 | — | — | EP | claimed |
| US-8357718-B2 | N-heterocyclyl- or cycloalkyl-N-(2-carboxy-5-aryl-3-thiophenyl)cycloalkanecarboxamides, e.g., 5-(3-fluorophenyl)-3-[isopropyl-(4-methylcyclohexanecarbonyl)amino]-thiophene-2-carboxylic acid; especially for prevention and treatment of HVC | VERTEX PHARMACEUTICALS (CANADA) INCORPORATED (CA) | 2013-01-22 | — | — | US | claimed |
| US-20120214766-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2012-08-23 | — | — | US | claimed |
| CN-102596913-A | Cannabinoid receptor modulators | ARENA PHARM INC | 2012-07-18 | — | — | CN | claimed |
| EP-2470508-A1 | CANNABINOID RECEPTOR MODULATORS | Arena Pharmaceuticals, Inc. (US) | 2012-07-04 | — | — | EP | claimed |
| WO-2011025541-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. (US) | 2011-03-03 | — | — | WO | claimed |
| EP-1722633-A2 | NEW INSECTICIDE COMPOSITION AND ITS USE, NAMELY FOR IMPREGNATION OF MOSQUITO NETS | Institut de Recherche pour le Développement ( IRD) (FR) | 2006-11-22 | — | — | EP | claimed |
| WO-2005079577-A2 | NOVEL INSECTICIDE COMPOSITION AND USE THEREOF PARTICULARLY FOR IMPREGNATING MOSQUITO NETS, FLY SCREENS AND THE LIKE | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2005-09-01 | — | — | WO | claimed |
| EP-0070204-B1 | CARBOXYLIC BETA-LACTAM COMPOUNDS AND THE PREPARATION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-19 | — | — | EP | claimed |
| EP-0089812-B1 | N-SUBSTITUTED PSEUDO-AMINOSUGARS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1986-10-01 | — | — | EP | claimed |
| US-3943121-A | Monoazo compounds from 3-aminobenzisothiazoles and substituted α-naphthylamine couplers | EASTMAN KODAK COMPANY (US) | 1976-03-09 | — | — | US | claimed |