SCHEMBL372741

SCHEMBL372741

CCC(C)N(CC)C(C)CC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435433 0.87 MEN1 (0.35) TSHR
SCHEMBL29296486 0.86 TSHR (0.31) TSHR
SCHEMBL17805498 0.82
SCHEMBL9950115 0.82 TSHR (0.40) TSHR
SCHEMBL21558638 0.82 ALDH1A1 (0.34) TSHR
SCHEMBL17431124 0.80 MEN1 (0.31)
SCHEMBL9949403 0.80 TSHR (0.38) TSHR
SCHEMBL7539397 0.76 TSHR (0.32) TSHR
SCHEMBL9950198 0.74 TSHR (0.33) TSHR
SCHEMBL22064879 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11237086-B2 System and method for extracting a target moiety from a sample using acoustic droplet ejection LABCYTE, INC. (US) 2022-02-01 US claimed
US-11021499-B2 Bis(6-methyl-3-sulphophenyl)(2-methylphenyl)phosphine, ammonium salt thereof, and method for producing same KURARAY CO., LTD. (JP) 2021-06-01 US claimed
US-20210088426-A1 SYSTEM AND METHOD FOR EXTRACTING A TARGET MOIETY FROM A SAMPLE USING ACOUSTIC DROPLET EJECTION LABCYTE, INC. 2021-03-25 US claimed
US-10696701-B2 Bis(6-methyl-3-sulphophenyl)phenylphosphine, ammonium salt thereof, and method for producing same KURARAY CO., LTD. (JP) 2020-06-30 US claimed
US-20190071460-A1 BIS(6-METHYL-3-SULPHOPHENYL)(2-METHYLPHENYL)PHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME HONDA ERIKO (JP) 2019-03-07 US claimed
EP-2980093-B1 BIS(6-METHYL-3-SULPHOPHENYL)(2-METHYLPHENYL)PHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2019-01-09 EP claimed
US-20180141967-A1 BIS(6-METHYL-3-SULPHOPHENYL)PHENYLPHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME KURARAY CO., LTD. (JP) 2018-05-24 US claimed
EP-2980092-B1 BIS(6-METHYL-3-SULPHOPHENYL)PHENYLPHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2017-10-04 EP claimed
US-20160052948-A1 BIS(6-METHYL-3-SULPHOPHENYL)(2-METHYLPHENYL)PHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME KURARAY CO., LTD. (JP) 2016-02-25 US claimed
US-20160052947-A1 BIS(6-METHYL-3-SULPHOPHENYL)PHENYLPHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME KURARAY CO., LTD. (JP) 2016-02-25 US claimed
EP-2980092-A1 BIS(6-METHYL-3-SULPHOPHENYL)PHENYLPHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME Kuraray Co., Ltd. (JP) 2016-02-03 EP claimed
US-9187504-B2 Method of making hydroxymethylphosphonate ICL-IP AMERICA INC. (US) 2015-11-17 US claimed
EP-2376507-B1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATES ICL IP AMERICA INC (US) 2013-05-15 EP claimed
US-8198341-B2 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. (US) 2012-06-12 US claimed
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom STOWELL JEFFREY K 2011-10-20 US claimed
EP-2376507-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM ICL-IP America Inc. (US) 2011-10-19 EP claimed
WO-2010080425-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM SUPRESTA LLC. (US) 2010-07-15 WO claimed
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. 2010-06-24 US claimed
EP-0467727-B1 Esterification process of hydroxybenzoic acids RHONE POULENC CHIMIE (FR) 1995-09-13 EP claimed
US-5260475-A Esterification of hydroxybenzoic acids RHONE-POULENC CHIMIE (FR) 1993-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom PFAS, PGM2, NEFM TSHR 3999/4885
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom PFAS, PGM2, NEFM TSHR 3999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.