Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13259616 | 0.82 | MAPK1 (0.48) | ADRA2ABACE1CYP3A4KMT2AGABRA1 | |
| SCHEMBL22587363 | 0.81 | ADRA2A (0.49) | KDM1AADRA2AGABRA1GABRG2GABRB3 | |
| SCHEMBL13259617 | 0.80 | CYP3A4 (0.49) | ADRA2AACHEALDH1A1CYP3A4KMT2A | |
| SCHEMBL2525541 | 0.77 | ADRA2A (0.47) | ADRA2ABACE1ACHEALDH1A1GABRA1 | |
| SCHEMBL13259619 | 0.76 | ACHE (0.49) | ADRA2AACHEALDH1A1KMT2AGABRA1 | |
| SCHEMBL3727746 | 0.76 | KDM1A (0.49) | KDM1AACHECA1CA2CA7 | |
| SCHEMBL15157577 | 0.74 | PRSS1 (0.39) | ADRA2APDK2 | |
| SCHEMBL15157918 | 0.73 | HDAC1 (0.37) | ADRA2APDK2 | |
| SCHEMBL12985400 | 0.73 | PDK2 (0.46) | ALDH1A1CYP3A4PDK2NPC1RAB9A | |
| SCHEMBL586923 | 0.73 | ADRA2A (0.43) | KDM1AADRA2AGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746230-A | Method for synthesis of 3-(3-methoxyphenyl)-3-trifluoromethyl-3H-diazirine | SHENGSHI TAIKE BIOLOG MEDICAL TECHNOLOGY SUZHOU CO LTD | 2012-10-24 | — | — | CN | disclosed |
| CN-102746230-A | Method for synthesis of 3-(3-methoxyphenyl)-3-trifluoromethyl-3H-diazirine | SHENGSHI TAIKE BIOLOG MEDICAL TECHNOLOGY SUZHOU CO LTD | 2012-10-24 | — | — | CN | disclosed |
| US-20100173793-A1 | PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS | UNIVERSITY OF WARWICK (GB) | 2010-07-08 | — | — | US | disclosed |
| US-20100173793-A1 | PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS | UNIVERSITY OF WARWICK (GB) | 2010-07-08 | — | — | US | disclosed |
| EP-1926992-A2 | PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS | THE UNIVERSITY OF WARWICK (GB) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007020453-A2 | PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS | UNIVERSITY OF WARWICK (GB) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007020453-A2 | PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS | UNIVERSITY OF WARWICK (GB) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173793-A1 | PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS | CLTA, CD40, DNPEP | KDM1A 4286/4885ADRA2A 4467/4885BACE1 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.